Maintained by:
- Group Leader: Mireia Coscollá
- Website creator: Paula Ruiz-Rodriguez
This is a webpage to show and disseminate results generated from Pathogenomics Lab
Our scientific approach is to study microbial pathogens in the context of their host and disease. To do this, we focus, but not exclusively, on the study of obligate intracellular bacteria with a wide host range to address host specificity as a virulence marker. To do this, we study bacterial infections with a wide range of hosts, such as tuberculosis and brucellosis. We will try to understand the basis of virulence in a given host, for a better understanding of the virulence of the pathogen. To approach this, we use a range of different omics where genomics is our main approach to study the evolution and molecular molecular epidemiology of the pathogen. But we also perform experimental infections to discover which genomic determinants are involved in different virulence readouts, using among other approaches transcriptomic of host and pathogen.
Additionally, we are studding viral relevant pathogens such as SARS-CoV-2 in multidisciplinary projects where we explore the evolution of SARS-CoV-2 to try to decipher the role of specific genomic determinants in virulence.